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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c40c7d388ae60a9ce4d5ccc3a6f8348e752c09bdda5a1bc2e9356111ef086771' 
  AND token = 'Cou2SmNdXdIfaORYcH2oDYfxQxEZRQSt5wTuPmTuM00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}