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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f33a1992e0f27c0b299d66c67b44f4f14692b5997f84290fd9711736f8fdba60' 
  AND token = 'znepW9tMSzzEstxCCM3+biWuZqA/13ulO+QYPnpl5SQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}