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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4261a37e69b6cb46bb5be64a536e59022638a51536e829fe70e16cffd08cfe7' 
  AND token = 'pKR/9UEaNk0KGd9ip2RV18qKDlSQjmxjfDzC98Jpado=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}