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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70adf1d018339ca19e28420e953e89f64f9b72b3e11b3c20758666ac2313a7f2' 
  AND token = 'fJI4skpSACaYJ6DM2bIVmp+guy5tERxYbBtX2F7cync=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}