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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c336d0ef3c3e60053c531e1fac84a1013b29346081d7a78125fc65d4c055b31' 
  AND token = 'knI61NuwvLdxItlQuM824E1eJ03pk7ShCY3pWq6L+wU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}