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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b01053b8f66a1680ff39800ad6632c76cc8efacbf519705939ed689f68914233' 
  AND token = '+SIj72hYEOD//aRu8O59PYC3MOqKU17m2DsPhg3nyiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}