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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74fd7ab17e4038e39d838771b7609bebce42ac544f0143f555a4d5aa3eb9aa71' 
  AND token = 'rSe0h+bR/4zPOhrzdG3yWUWvmH3nb4fM2Zw3OkuZ1w8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}