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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eeb60b380d1a0cab56dd7caa6df1cbefc695d92b4535a73bd8ac089e7646c4f' 
  AND token = 'eNLUffa8fsak4G1F3Ag4JwNZuEfFrUGZajrggGegNHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}