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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2afe810a25a8db2e6c0a037d73071f9a7f0faee33c4642e41a499f5f159269b7' 
  AND token = 'lEMdqXujJ3/u1IqCW3pJUecB+xrgdeMRoP7EfVFZX9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}