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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c6421064cf0d25b5af47ca36670b02ecd03494745b26f4207d6ac43c6aed071' 
  AND token = 'QsKxyLBWxxJMZx5NG35cT9wzsr7rlkBCslwT/n2dx4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}