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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c500da9a79b4f9009f9dfb3d8f611b99f964930aafd7ce412c64d2edd7eb0cd' 
  AND token = 'N0DBIVXRXdbwJXzDqQcAD2zCP3Y9PRzvP68dlm+WmkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}