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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '543a10cdf3428d1c7f85a8a2063591b0fb7b3fe0703481d17505096291ff7b14' 
  AND token = 'xl3INxjx0Xu+GKS+R087gXK9lA5e2IOJRPoISI0bhvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}