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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e7307ef1bf479be5b3f6ca3471c0917bc654c9a8cc92b5f21a55a58102b030c' 
  AND token = 'cE6pPV82PVWAlAHOVBAD9eQzIU3HKk/aLyVLcINb7Zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}