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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '426c20ffbb0ae0b40b6f1e7de7c0f0fd5e2c9923055152ac95574801b5ce1648' 
  AND token = 'ER+H6Oi38cezfwSSD1MPip78uNwXT6xjKayiGHKnK8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}