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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88394a7068b72c4e771696ea2bc264d9333cebee16152b6fd109c70aec7d8129' 
  AND token = 'P+AVJOkx3rAFdlSOcFdzRBvZKG03vCJ6LV38izSt3SE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}