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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c81c55202c353dd78dbb0e911523270e96e072a8c447fea95aa93ed901c4200' 
  AND token = 'yVc4LBR7f/3FhvFFl6xs2OXfQF6oDGSOWUEtGE1k5Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}