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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0416db28292c53e99668d07ec1755f4925a3a6a47ecde3078cc2a4264cfac1c6' 
  AND token = 'xosDi+AEm5CfrqR3xSXcPgdfpp1yIcAp36aZTqA4nLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}