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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5462b9da60b69482d204a19e94551f9ec29a165c017e134e6cf6ba48337dd26a' 
  AND token = '4x/snRbHU9ULy0EkgSJ8btwXVYcV3khQULhaHAqs5mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}