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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26e5fad5650259061a9f328e34cff395a019bc5e212fefb3df9a42b42b3f7484' 
  AND token = 'Sl5dSVEuEnUcqPWppoVLrBjW9mNELWhwEot0ybY/Wp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}