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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cd9777148ed0a4f73506c16fd627aac5cc6896c7e337a0accc4cf88436a87cb' 
  AND token = 'Ir45P46nGUTlXrV3wA7mGJ9LkNzZrSmuL6qAfMlJNTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}