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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52f02f9f1a0b81575edbe0c3712008ce89b689bb99a95db46686415f84a36c16' 
  AND token = 'FFv5vo80x0rcqCR680q/LC4Degr8RXRyuzgRcTdH/pE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}