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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99c05303dd7eb6fd602c872eaef272bf37a64e7cb15f0e069a201ad8c49254bc' 
  AND token = 'ZZ7HZHQHqLC1MEbnY9SKF2165Ru8syN+Iga7XkfgXOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}