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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea4db4e0ed16c54a861a85359a7a624fee9df5372daf7d87efd1515833aff0c2' 
  AND token = 'XZasyLHB+lkgeCQvsY0lAQ798Mf84FceZiEaBVFv7bI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}