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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '531c3f303b7a6d644f3daae3d8eb6c0ba0f23debb53364689344a2557dc8d72c' 
  AND token = 'kW03rOGIgQaEaFz1OKq7zjL34VUMCnLAbwMWihhQShc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}