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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e8b7b4f1ed0acfbedcc8ceb331c786007db22cb93502fe9178e7c7811bbb271' 
  AND token = 'mJGowbn2s8oxC6fc6ebJ3+amO5jxgsBOGEZTvMpbSLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}