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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7073ef64f3cea3bf50fcd7b681fc5f1b9ddaea7ae80aff040fbb557f58d1b75a' 
  AND token = 'jL3c49+0Gbal2MLMwIq8+ABQ0L2dUcOseycogbwnO1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}