Sandbox

SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c857b27511949060600dc52cad6c70e2a6679678dce27ece278440a3fd1d2be' 
  AND token = 'YUQmUlf/p0QP1JWHRK1EtRbsb+/LYW+kWQcuJSyzSMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}