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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41fe122f90c1e23c826de89b0de9493718f9436de82fc73d3fc27f518c08bc9d' 
  AND token = 'XMN+b3l19ym9c1Z4ewJe/YYmT3uQ8Bu1ZTCYAa1uJPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}