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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '166278b89bab0539d6b7e8eb740faac49698fd00f231c2f4a9d41740703a3cb8' 
  AND token = '6UZWMHdNfF7ux3SV6lHagnDKyNoHe9Q/PsiJ55OMnJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00191

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}