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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f30c816c22d8cc3d6fb566a540e83f6b0d8b10613f683c399e44d441f80fa694' 
  AND token = '+ZteJkGVE1CGZddZN0MzrPQtNjmCgq/Fg3JdXc+yjTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}