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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1265372f562e59f85ef7fc3e33a7d78a3eb0700aa489a4fb3e1d131075a8d0b0' 
  AND token = 'on+iUie/H3RC8PiKPvAUuJOgcRp2wQf/cyK99uDRI2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}