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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d7f79c02a2b68a435a0568bb8179567415e67cc3acc1a21c82c3629f2dbc31' 
  AND token = 'TvQNnUf1O0tL7iPb1u825hygy+jnx4FthxDkQkpaprM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}