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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f4c9189d5a9b703fe711d6e15d37cb1f684605d3839e6e267539cc7b759b2e7' 
  AND token = 'eReu25x7WeaxQ1GlODvh5mZyn8iB7/NvtwYUwQwj8o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}