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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0371fc20cbb9d9b5a80bff6072843d1a0de79f35116cf6e1d6ea9f60d29deddf' 
  AND token = 'ugLeDm2c9CA+212qI/SE0spFUPwUVlSyZuPMO1hboxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}