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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67070bb46cb677ac1c0267e1f7cf680af15667bd4f3ac4cb5101c338e37a29e0' 
  AND token = 'M7b/4W/LGsNq1d+xvPF5Ap/ZvyUVFpBhVLMGNlvsMNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}