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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c011a8075f76916f82f6e6834c3f8f6df5ee837321ada16fb7bfafcb5a3e0469' 
  AND token = 'EkCm4lE6Xo0UVKRZX8fzworagO4nl/+rHatD+0HkBkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}