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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e5a5c8f4b100c642043c5f77f712cc755fc67ba09de8e4a1524242474570211' 
  AND token = '5VUCLd+P5Ngmt71LcKKbSyVh0fj+iyCl8RKfGrQBgUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}