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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5169d75d6106e92d5ad84f3cd96db9dd595a91aa45cb2710818244d13496428d' 
  AND token = 'bXOtBsSsNgGIy/5UF86SYQMSEst/6WGM8Xd30nLNGOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}