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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c38b528470f68a991087cdaa7867ef5acdab44134805fd48c9a90255832297cf' 
  AND token = 'M6o+nAc/dyJUVWsK0n7PtNWbr3npFsviDDOBahuIkt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}