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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb69086facf8bc8299c3870f3ede4186a5cbeddf62807917a71bf10a4726e213' 
  AND token = 'Duv8ewgRi+piHVcUy9OTmusDQVEnEUipQ+eyP6aHOQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}