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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77b6c478be2fe2a7a55b1113ed25fcdf3a8102f6b0b262440cc73f8e1442fe0a' 
  AND token = 'XgnQRCmirxCXyvbt8rYUx7furG13Wk2ZuM/N8bFXd9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}