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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5faaa3cd378bd401816329949012ec4f7f6a1baf9c7cf366dbdb18483dc994ae' 
  AND token = '+a2ezJ1HFcD5+IJjFjKC4hEddXmrb4SMJWQYust/AQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}