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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd45311487ab290c2aba7140af6cdcc65350a1d4378a27193665e0c20b174ef93' 
  AND token = 'mf/x2SST9O0kJgvmuwc4ASJdWwDWWHFcSC1/0jKgICE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}