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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4efb06b10fee23c34fc39a680c255198c2796e2995df57ed6e352d5a0c576c26' 
  AND token = '1ocjDgELnrgCKZMYTumbdSdRt4g93ct3sG/aOi982fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}