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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7817cc4dad7e48b9145c06df3916996e45d9f2c7115f42a4b45b784ea1020b54' 
  AND token = 'TxC4+EezQbnetrz6l3GeDhTNR2sw+dSiFe6KqbT9Cwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}