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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e307617b3737a78f2594eaf9e23c04ea4fbf603f0e44c7164c27a167e2b25451' 
  AND token = '4EMZjPEQlRGWRk96DicEFrnOTwwStVf/HCEJ9s3WRtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}