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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12650155588cff9c61d28f39aa2921a80f08cfc4b96c86791036804232b99223' 
  AND token = 'fu1/pix4/vL0X29GkiI/SwXmGKLLkIkIBO9tb58hen8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}