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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1364470adef19cac0a42573d75178dd3d51620ec306ffe05a4077151e8e63fc3' 
  AND token = 'pf/s5k7f6GjMmqC3mUyOFOoKYN27+oA8bnOxK+ctSHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}