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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef92ce2d37caef3b4e005f9b7890044a7a4a48c942ac8b15aa39d9ea7270730' 
  AND token = 's+yNXo5qSpkdfZpWR5eyFJSJqMX7w1A2k+sfeuLvcw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}