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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de9ac87e876e7b94d4083cab17dabd6636f85b898d1a2ecc8c6b9df4f5739800' 
  AND token = 'h+kUGtMQ6HoS4tP9xxQPCc584hoDB7PxVuBlHnIIK+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}